抄読会

59th (Jan. 8. 2025. 18:15 - )  Toshikatsu Ikeda

Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion

Jiang N, Xie B, Xiao W, Fan M, Xu S, Duan Y, Hamsafar Y, Evans AC, Huang J, Zhou W, Lin X, Ye N, Wanggou S, Chen W, Jing D, Fragoso RC, Dugger BN, Wilson PF, Coleman MA, Xia S, Li X, Sun LQ, Monjazeb AM, Wang A, Murphy WJ, Kung HJ, Lam KS, Chen HW, Li JJ.

Nat Commun. 2022 Mar 21;13(1):1511.

58th (Dec. 11. 2024. 18:15 - )  Yuki Katoh

In vivo dendritic cell reprogramming for cancer immunotherapy

Ascic E, Åkerström F, Sreekumar Nair M, Rosa A, Kurochkin I, Zimmermannova O, Catena X, Rotankova N, Veser C, Rudnik M, Ballocci T, Schärer T, Huang X, de Rosa Torres M, Renaud E, Velasco Santiago M, Met Ö, Askmyr D, Lindstedt M, Greiff L, Ligeon LA, Agarkova I, Svane IM, Pires CF, Rosa FF, Pereira CF.

Science. 2024 Oct 18;386(6719):eadn9083.

57th (Nov. 6. 2024. 18:15 - )  Masaki Sugawara

Fate induction in CD8 CAR T cells through asymmetric cell division

Berry CT, Frazee CS, Herman PJ, Chen S, Chen A, Kuo Y, Ellebrecht CT.

Semin Immunopathol. 2025 Jan 16;47(1):7.

56th (Oct. 23. 2024. 18:15 - )  Toshihiro Sugi

SCD1 inhibition enhances the effector functions of CD8+ T cells via ACAT1-dependent reduction of esterified cholesterol.

Sugi T, Katoh Y, Ikeda T, Seta D, Iwata T, Nishio H, Sugawara M, Kato D, Katoh K, Kawana K, Yaguchi T, Kawakami Y, Hirai S.

Cancer Sci. 2024 Jan;115(1):48-58.

55th (Oct. 9. 2024. 18:15 - )  Shun Otsuka

Inhibition of IL-11 signalling extends mammalian healthspan and lifespan

Widjaja AA, Lim WW, Viswanathan S, Chothani S, Corden B, Dasan CM, Goh JWT, Lim R, Singh BK, Tan J, Pua CJ, Lim SY, Adami E, Schafer S, George BL, Sweeney M, Xie C, Tripathi M, Sims NA, Hübner N, Petretto E, Withers DJ, Ho L, Gil J, Carling D, Cook SA.

Nature. 2024 Aug;632(8023):157-165.

54th (Sep. 25. 2024. 18:15 - )  Naoyuki Hatayama

Exogenous carbon monoxide promotes GPX4-dependent ferroptosis through ROS/GSK3β axis in non-small cell lung cancer

Kim YJ, Kim HJ, Lee SG, Kim DH, In Jang S, Go HS, Lee WJ, Seong JK.Cao W, Sun M, Yu KN, Zhao L, Feng Y, Tan C, Yang M, Wang Y, Zhu F, Chen L, Nie L, Zhao Y, Chen G, Han W.

Cell Death Discov. 2024 Jan 23;10(1):42.

53th (Sep. 11. 2024. 18:15 - )  Eri Nanizawa

Aerobic exercise for eight weeks provides protective effects towards liver and cardiometabolic health and adipose tissue remodeling under metabolic stress for one week: A study in mice

Kim YJ, Kim HJ, Lee SG, Kim DH, In Jang S, Go HS, Lee WJ, Seong JK.

Metabolism. 2022 May;130:155178.

52th (Aug. 28. 2024. 18:15 - )  Tomonori Harada

Resilient anatomy and local plasticity of naive and stress haematopoiesis

Wu Q, Zhang J, Kumar S, Shen S, Kincaid M, Johnson CB, Zhang YS, Turcotte R, Alt C, Ito K, Homan S, Sherman BE, Shao TY, Slaughter A, Weinhaus B, Song B, Filippi MD, Grimes HL, Lin CP, Ito K, Way SS, Kofron JM, Lucas D.

Nature. 2024 Mar;627(8005):839-846.

51th (Jul. 31. 2024. 18:15 - )  Daichi Seta

Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers

Beck JD, Diken M, Suchan M, Streuber M, Diken E, Kolb L, Allnoch L, Vascotto F, Peters D, Beißert T, Akilli-Öztürk Ö, Türeci Ö, Kreiter S, Vormehr M, Sahin U.

Cancer Cell. 2024 Apr 8;42(4):568-582.e11.

50th (Jul. 17. 2024. 18:15 - )  Kenta Nagahori

Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1

Luo JQ, Yang TW, Wu J, Lai HH, Zou LB, Chen WB, Zhou XM, Lv DJ, Cen SR, Long ZN, Mao YY, Zheng PX, Su XH, Xian ZY, Shu FP, Mao XM.

Cell Death Dis. 2023 Aug 4;14(8):502.

49th (Jun. 26. 2024. 18:15 - )  Toshikatsu Ikeda

Lipase regulation of cellular fatty acid homeostasis as a Parkinson's disease therapeutic strategy

Fanning S, Cirka H, Thies JL, Jeong J, Niemi SM, Yoon J, Ho GPH, Pacheco JA, Dettmer U, Liu L, Clish CB, Hodgetts KJ, Hutchinson JN, Muratore CR, Caldwell GA, Caldwell KA, Selkoe D.

NPJ Parkinsons Dis. 2022 Jun 9;8(1):74. 

48th (Jun. 12. 2024. 18:15 - )  Yuki Katoh

Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

Kumagai S, Koyama S, Itahashi K, Tanegashima T, Lin YT, Togashi Y, Kamada T, Irie T, Okumura G, Kono H, Ito D, Fujii R, Watanabe S, Sai A, Fukuoka S, Sugiyama E, Watanabe G, Owari T, Nishinakamura H, Sugiyama D, Maeda Y, Kawazoe A, Yukami H, Chida K, Ohara Y, Yoshida T, Shinno Y, Takeyasu Y, Shirasawa M, Nakama K, Aokage K, Suzuki J, Ishii G, Kuwata T, Sakamoto N, Kawazu M, Ueno T, Mori T, Yamazaki N, Tsuboi M, Yatabe Y, Kinoshita T, Doi T, Shitara K, Mano H, Nishikawa H.

Cancer Cell. 2022 Feb 14;40(2):201-218.e9.

47th (May. 29. 2024. 18:15 - )  Masaki Sugawara

Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy

Wang C, Zeng Q, Gül ZM, Wang S, Pick R, Cheng P, Bill R, Wu Y, Naulaerts S, Barnoud C, Hsueh PC, Moller SH, Cenerenti M, Sun M, Su Z, Jemelin S, Petrenko V, Dibner C, Hugues S, Jandus C, Li Z, Michielin O, Ho PC, Garg AD, Simonetta F, Pittet MJ, Scheiermann C.

Cell. 2024 May 23;187(11):2690-2702.e17.

46th (May. 15. 2024. 18:15 - )  Shun Otsuka

A Piezo1/KLF15/IL-6 axis mediates immobilization-induced muscle atrophy

Hirata Y, Nomura K, Kato D, Tachibana Y, Niikura T, Uchiyama K, Hosooka T, Fukui T, Oe K, Kuroda R, Hara Y, Adachi T, Shibasaki K, Wake H, Ogawa W.

J Clin Invest. 2022 May 16;132(10):1-13.

45th (Apr. 24. 2024. 18:15 - )  Naoyuki Hatayama

Design and testing of a humanized porcine donor for xenotransplantation

Anand RP, Layer JV, Heja D, Hirose T, Lassiter G, Firl DJ, Paragas VB, Akkad A, Chhangawala S, Colvin RB, Ernst RJ, Esch N, Getchell K, Griffin AK, Guo X, Hall KC, Hamilton P, Kalekar LA, Kan Y, Karadagi A, Li F, Low SC, Matheson R, Nehring C, Otsuka R, Pandelakis M, Policastro RA, Pols R, Queiroz L, Rosales IA, Serkin WT, Stiede K, Tomosugi T, Xue Y, Zentner GE, Angeles-Albores D, Chris Chao J, Crabtree JN, Harken S, Hinkle N, Lemos T, Li M, Pantano L, Stevens D, Subedar OD, Tan X, Yin S, Anwar IJ, Aufhauser D, Capuano S, Kaufman DB, Knechtle SJ, Kwun J, Shanmuganayagam D, Markmann JF, Church GM, Curtis M, Kawai T, Youd ME, Qin W.

Nature. 2023 Oct;622(7982):393-401. 

44th (Mar. 27. 2024. 18:15 - )  Tomonori Harada

On the genetic basis of tail-loss evolution in humans and apes

Xia B, Zhang W, Zhao G, Zhang X, Bai J, Brosh R, Wudzinska A, Huang E, Ashe H, Ellis G, Pour M, Zhao Y, Coelho C, Zhu Y, Miller A, Dasen JS, Maurano MT, Kim SY, Boeke JD, Yanai I.

Nature. 2024 Feb;626(8001):1042-1048.

43th (Mar. 27. 2024. 18:15 - )  Daichi Seta

Combined administration of lauric acid and glucose improved cancer-derived cardiac atrophy in a mouse cachexia model

Nukaga S, Mori T, Miyagawa Y, Fujiwara-Tani R, Sasaki T, Fujii K, Mori S, Goto K, Kishi S, Nakashima C, Ohmori H, Kawahara I, Luo Y, Kuniyasu H.

Cancer Sci. 2020 Dec;111(12):4605-4615.

42th (Mar. 6. 2024. 18:15 - )  Toshihiro Sugi

Monounsaturated and Diunsaturated Fatty Acids Sensitize Cervical Cancer to Radiation Therapy

Muhammad N, Ruiz F, Stanley J, Rashmi R, Cho K, Jayachandran K, Zahner MC, Huang Y, Zhang J, Markovina S, Patti GJ, Schwarz JK.

Cancer Res. 2022 Dec 16;82(24):4515-4527. 

41th (Feb. 21. 2024. 18:15 - )  Kenta Nagahori

Serum Neuroinflammatory Disease-Induced Central Nervous System Proteins Predict Clinical Onset of Experimental Autoimmune Encephalomyelitis

Raphael I, Webb J, Gomez-Rivera F, Chase Huizar CA, Gupta R, Arulanandam BP, Wang Y, Haskins WE, Forsthuber TG.

Front Immunol. 2017 Jul 17;8:812.

40th (Feb. 7. 2024. 18:15 - )  Toshikatsu Ikeda

Unraveling the mechanisms of deep-brain stimulation of the internal capsule in a mouse model

van den Boom BJG, Elhazaz-Fernandez A, Rasmussen PA, van Beest EH, Parthasarathy A, Denys D, Willuhn I.

Nat Commun. 2023 Sep 4;14(1):5385. 

39th (Jan. 24. 2024. 18:15 - )  Yuki Katoh

Regulatory T cells shield muscle mitochondria from interferon-γ-mediated damage to promote the beneficial effects of exercise

Langston PK, Sun Y, Ryback BA, Mueller AL, Spiegelman BM, Benoist C, Mathis D.

Sci Immunol. 2023 Nov 3;8(89):eadi5377. 

38th (Jan. 10. 2024. 18:15 - )  Shun Otsuka

Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination

Sadaki S, Fujita R, Hayashi T, Nakamura A, Okamura Y, Fuseya S, Hamada M, Warabi E, Kuno A, Ishii A, Muratani M, Okada R, Shiba D, Kudo T, Takeda S, Takahashi S.

Cell Rep. 2023 Apr 25;42(4):112289. 

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