抄読会

37th (Dec. 13. 2023. 18:15 - )  Tomonori Harada

Hypoxia-inducible lipid droplet-associated induces DGAT1 and promotes lipid storage in hepatocytes.

de la Rosa Rodriguez MA, Deng L, Gemmink A, van Weeghel M, Aoun ML, Warnecke C, Singh R, Borst JW, Kersten S.

Mol Metab. 2021 May;47:101168.

36th (Nov. 29. 2023. 18:15 - )  Daichi Seta

The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity.

Baumgartner CK, Ebrahimi-Nik H, Iracheta-Vellve A, Hamel KM, Olander KE, Davis TGR, McGuire KA, Halvorsen GT, Avila OI, Patel CH, Kim SY, Kammula AV, Muscato AJ, Halliwill K, Geda P, Klinge KL, Xiong Z, Duggan R, Mu L, Yeary MD, Patti JC, Balon TM, Mathew R, Backus C, Kennedy DE, Chen A, Longenecker K, Klahn JT, Hrusch CL, Krishnan N, Hutchins CW, Dunning JP, Bulic M, Tiwari P, Colvin KJ, Chuong CL, Kohnle IC, Rees MG, Boghossian A, Ronan M, Roth JA, Wu MJ, Suermondt JSMT, Knudsen NH, Cheruiyot CK, Sen DR, Griffin GK, Golub TR, El-Bardeesy N, Decker JH, Yang Y, Guffroy M, Fossey S, Trusk P, Sun IM, Liu Y, Qiu W, Sun Q, Paddock MN, Farney EP, Matulenko MA, Beauregard C, Frost JM, Yates KB, Kym PR, Manguso RT.

Nature. 2023 Oct;622(7984):850-862. 

35th (Oct. 25. 2023. 18:15 - )  Toshihiro Sugi

FASN promotes lymph node metastasis in cervical cancer via cholesterol reprogramming and lymphangiogenesis.

Du Q, Liu P, Zhang C, Liu T, Wang W, Shang C, Wu J, Liao Y, Chen Y, Huang J, Tan H, Zhao Y, Xia M, Liu J, Yao S.

Cell Death Dis. 2022 May 21;13(5):488.

34th (Oct. 11. 2023. 18:15 - )  Kenta Nagahori

Effects of aging and macrophages on mice stem Leydig cell proliferation and differentiation in vitro.

Shao J, Wang J, Wen X, Xie J, Huang F, Guan X, Hao X, Duan P, Chen C, Chen H.

Front Endocrinol (Lausanne). 2023 Mar 27;14:1139281.

33th (Sep. 27. 2023. 18:15 - )  Toshikatsu Ikeda

Pathological pallidal beta activity in Parkinson's disease is sustained during sleep and associated with sleep disturbance.

Yin Z, Ma R, An Q, Xu Y, Gan Y, Zhu G, Jiang Y, Zhang N, Yang A, Meng F, Kühn AA, Bergman H, Neumann WJ, Zhang J.

Nat Commun. 2023 Sep 5;14(1):5434. 

32th (Sep. 13. 2023. 18:15 - )  Yuki Katoh

Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy.

Wellhausen N, O'Connell RP, Lesch S, Engel NW, Rennels AK, Gonzales D, Herbst F, Young RM, Garcia KC, Weiner D, June CH, Gill SI.

Sci Transl Med. 2023 Sep 20;15(714):eadi1145.

31th (Aug. 30. 2023. 18:15 - )  Shun Otsuka

The mechanosensitive ion channel PIEZO1 is expressed in tendons and regulates physical performance.

Nakamichi R, Ma S, Nonoyama T, Chiba T, Kurimoto R, Ohzono H, Olmer M, Shukunami C, Fuku N, Wang G, Morrison E, Pitsiladis YP, Ozaki T, D'Lima D, Lotz M, Patapoutian A, Asahara H.

Sci Transl Med. 2022 Jun;14(647):eabj5557. 

30th (Jul. 19. 2023. 18:15 - )  Tomonori Harada

Vitrification and nanowarming enable long-term organ cryopreservation and life-sustaining kidney transplantation in a rat model.

Han Z, Rao JS, Gangwar L, Namsrai BE, Pasek-Allen JL, Etheridge ML, Wolf SM, Pruett TL, Bischof JC, Finger EB.

Nat Commun. 2023 Jun 9;14(1):3407.

29th (Jul. 5. 2023. 18:15 - )  Daichi Seta

Metabolic support of tumour-infiltrating regulatory T cells by lactic acid.

Watson MJ, Vignali PDA, Mullett SJ, Overacre-Delgoffe AE, Peralta RM, Grebinoski S, Menk AV, Rittenhouse NL, DePeaux K, Whetstone RD, Vignali DAA, Hand TW, Poholek AC, Morrison BM, Rothstein JD, Wendell SG, Delgoffe GM.

Nature. 2021 Mar;591(7851):645-651. 

28th (Jun. 21. 2023. 18:15 - )  Toshihiro Sugi

Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis.

Geng F, Cheng X, Wu X, Yoo JY, Cheng C, Guo JY, Mo X, Ru P, Hurwitz B, Kim SH, Otero J, Puduvalli V, Lefai E, Ma J, Nakano I, Horbinski C, Kaur B, Chakravarti A, Guo D.

Clin Cancer Res. 2016 Nov 1;22(21):5337-5348.

27th (May. 24. 2023. 18:15 - )  Naoyuki Hatayama

An integrated perfusion machine preserves injured human livers for 1 week

Carpino G, Del Ben M, Pastori D, Carnevale R, Baratta F, Overi D, Francis H, Cardinale V, Onori P, Safarikia S, Cammisotto V, Alvaro D, Svegliati-Baroni G, Angelico F, Gaudio E, Violi F.

Nat Biotechnol. 2020 Feb;38(2):189-198.

26th (May. 10. 2023. 18:15 - )  Eri Nanizawa

Increased Liver Localization of Lipopolysaccharides in Human and Experimental NAFLD

Carpino G, Del Ben M, Pastori D, Carnevale R, Baratta F, Overi D, Francis H, Cardinale V, Onori P, Safarikia S, Cammisotto V, Alvaro D, Svegliati-Baroni G, Angelico F, Gaudio E, Violi F.

Hepatology. 2020 Aug;72(2):470-485.

25th (Apr. 20. 2023. 18:15 - )  Kenta Nagahori

Single-cell analysis of human testis aging and correlation with elevated body mass index. 

Nie X, Munyoki SK, Sukhwani M, Schmid N, Missel A, Emery BR, DonorConnect, Stukenborg JB, Mayerhofer A, Orwig KE, Aston KI, Hotaling JM, Cairns BR, Guo J.

Dev Cell. 2022 May 9;57(9):1160-1176.e5. 

24th (Apr. 12. 2023. 18:15 - )  Toshikatsu Ikeda

A brain network for deep brain stimulation induced cognitive decline in Parkinson's disease.

Reich MM, Hsu J, Ferguson M, Schaper FLWVJ, Joutsa J, Roothans J, Nickl RC, Frankemolle-Gilbert A, Alberts J, Volkmann J, Fox MD.

Brain. 2022 May 24;145(4):1410-1421. 

23th (Mar. 22. 2023. 18:15 - )  Yuki Katoh

Highly immunogenic cancer cells require activation of the WNT pathway for immunological escape

Takeuchi Y, Tanegashima T, Sato E, Irie T, Sai A, Itahashi K, Kumagai S, Tada Y, Togashi Y, Koyama S, Akbay EA, Karasaki T, Kataoka K, Funaki S, Shintani Y, Nagatomo I, Kida H, Ishii G, Miyoshi T, Aokage K, Kakimi K, Ogawa S, Okumura M, Eto M, Kumanogoh A, Tsuboi M, Nishikawa H.

Sci Immunol. 2021 Nov 12;6(65):eabc6424. 

22th (Mar. 8. 2023. 18:15 - )  Hoshizora Ichinose

Oxidative stress-induced S100B accumulation converts myoblasts into brown adipocytes via an NF-κB/YY1/miR-133 axis and NF-κB/YY1/BMP-7 axis

Morozzi G, Beccafico S, Bianchi R, Riuzzi F, Bellezza I, Giambanco I, Arcuri C, Minelli A, Donato R.

Cell Death Differ. 2017 Dec;24(12):2077-2088.

21th ( Feb. 22. 2022. 18:00 - )  Shun Otsuka

Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1.

Brett JO, Arjona M, Ikeda M, Quarta M, de Morrée A, Egner IM, Perandini LA, Ishak HD, Goshayeshi A, Benjamin DI, Both P, Rodríguez-Mateo C, Betley MJ, Wyss-Coray T, Rando TA.

Nat Metab. 2020 Apr;2(4):307-317. 

20th ( Feb. 8. 2022. 18:00 - )  Tomonori Harada

A discrete neuronal circuit induces a hibernation-like state in rodents.

Takahashi TM, Sunagawa GA, Soya S, Abe M, Sakurai K, Ishikawa K, Yanagisawa M, Hama H, Hasegawa E, Miyawaki A, Sakimura K, Takahashi M, Sakurai T.

Nature. 2020 Jul;583(7814):109-114.

19th ( Jan. 18. 2022. 18:00 - )  Daichi Seta

Alterations in Circulating Fatty Acid Are Associated With Gut Microbiota Dysbiosis and Inflammation in Multiple Sclerosis.

Saresella M, Marventano I, Barone M, La Rosa F, Piancone F, Mendozzi L, d'Arma A, Rossi V, Pugnetti L, Roda G, Casagni E, Cas MD, Paroni R, Brigidi P, Turroni S, Clerici M.

Front Immunol. 2020 Jul 7;11:1390.

18th ( Jan. 11. 2022. 18:00 - )  Toshihiro Sugi

Cholesterol Induces CD8+ T Cell Exhaustion in the Tumor Microenvironment.

Ma X, Bi E, Lu Y, Su P, Huang C, Liu L, Wang Q, Yang M, Kalady MF, Qian J, Zhang A, Gupte AA, Hamilton DJ, Zheng C, Yi Q.

Cell Metab. 2019 Jul 2;30(1):143-156.e5.

参加希望者のご連絡をお待ちしております。