Publication

Shigeyuki Uno, Ph.D. (-2003)

  1. Uno S, Wang B, Shertzer HG, Nebert DW, Dalton TP. Balancer-Cre transgenic mouse germ cells direct the incomplete resolution of a tri-loxP-targeted Cyp1a1 allele, producing a conditional knockout allele. Biochem Biophys Res Commun 312: 494-499, 2003
  2. Watanabe Y, Takahashi H, Uno S, Takano S, Nakagawa S. Expression of type 1 plasminogen activator inhibitor and nitric oxide generation in ischemic preconditioning of rat liver. Hepatol Res 25: 343-53, 2003
  3. Senft AP, Dalton TP, Nebert DW, Genter MB, Puga A, Hutchinson RJ, Kerzee JK, Uno S, Shertzer HG. Mitochondrial reactive oxygen production is dependent on the aromatic hydrocarbon receptor. Free Radic Biol Med 33:1268-78, 2002
  4. Uno S, Dalton TP, Shertzer HG, Genter MB, Warshawsky D, Talaska G, Nebert DW. Benzo[a]pyrene-induced toxicity: paradoxical protection in Cyp1a1(-/-) knockout mice having increased hepatic BaP-DNA adduct levels. Biochem Biophys Res Commun 289: 1049-1056, 2001
  5. Noguchi T, Matsuyama S, Akao M, Hagiwara H, Uno S, Seki T, Ariga T. Induction of hepatic tissue-type plasminogen activator and type 1 plasminogen activator-inhibitor gene expressions and appearance of their translation products in the bile following acute liver injury in rats. Thromb Res 104: 283-291, 2001
  6. Takahashi H, Uno S, Watanabe Y, Arakawa K, Nakagawa S. Expression of nerve growth factor-induced type 1 plasminogen activator inhibitor (PAI-1) mRNA is inhibited by genistein and wortmannin. Neuroreport 11: 1111-1115, 2000
  7. Uno S, Nakamura M, Ohomagari Y, Matsuyama S, Seki T, Ariga T. Regulation of tissue-type plasminogen activator (tPA) and type-1 plasminogen activator inhibitor (PAI-1) gene expression in rat hepatocytes in primary cultured. J Biochem 123: 806-812, 1998
  8. Uno S, Nakamura M, Seki T, Ariga T. Induction of tissue-type plasminogen activator (tPA) and type-1 plasminogen activator inhibitor (PAI-1) as early growth responses in rat hepatocytes in primary culture. Biochem Biophys Res Commun 239: 123-128, 1997
  9. Seki T, Imai H, Uno S, Ariga T, Gelehrter TD. Production of tissue-type plasminogen activator (tPA) and type-1 plasminogen activator inhibitor (PAI-1) in mildly cirrhotic rat liver. Thromb Haemost 75: 801-807, 1996

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