Kaneko E, Matsuda M, Yamada Y, Tachibana Y, Shimomura I, Makishima M. Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist. J Biol Chem 278: 36091-36098, 2003
Iwaki M, Matsuda M, Maeda N, Funahashi T, Matsuzawa Y, Makishima M, Shimomura I. Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors. Diabetes 52: 1655-1663, 2003
Inaba T, Matsuda M, Shimamura M, Takei N, Terasaka N, Ando Y, Yasumo H, Koishi R, Makishima M, Shimomura I. Angiopoietin-like protein 3 (Angptl3) mediates hypertriglyceridemia induced by the liver X receptor. J Biol Chem 278: 21344-21351, 2003
Choi M, Yamamoto K, Itoh T, Makishima M, Mangelsdorf DJ, Moras D, DeLuca HF, Yamada S. Interaction between vitamin D receptor and vitamin D ligands: two-dimensional alanine scanning mutational analysis. Chem Biol 10: 261-270, 2003
Shimamura M, Matsuda M, Kobayashi S, Ando Y, Ono M, Koishi R, Furukawa H, Makishima M, Shimomura I. Angiopoietin-like protein 3, a hepatic secretory factor, activates lipolysis in adipocytes. Biochem Biophys Res Commun 301: 604-609, 2003
Makishima M, Lu TT, Xie W, Whitfield GK, Domoto H, Evans RM, Haussler MR, Mangelsdorf DJ. Vitamin D receptor as an intestinal bile acid sensor. Science 296: 1313-1316, 2002
Denson LA, Sturm E, Echevarria W, Zommerman TL, Makishima M, Mangelsdorf DJ, Karpen SJ. The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp. Gastroenterology 121: 140-147, 2001
Ananthanarayanan M, Balasubramanian N, Makishima M, Mangelsdorf DJ, Suchy, F. J. Human bile salt export pump (BSEP) promoter is transactivated by the farnesoid X receptor/bile acid receptor (FXR/BAR). J Biol Chem 276: 28857-28865, 2001
Lu TT, Makishima M, Repa JJ, Schoonjans K, Kerr TA, Auwerx J, Mangelsdorf DJ. Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors. Mol Cell 6: 507-515, 2000
Makishima M, Okamoto AY, Repa JJ, Tu H, Learned RM, Luk A, Hull MV, Lustig KD, Mangelsdorf DJ, Shan B. Identification of a nuclear receptor for bile acids. Science 284: 1362-1365, 1999
Makishima M, Shudo K, Honma Y. Greater synergism of retinoic acid receptor (RAR) agonists with vitamin D3 than that of retinoid X receptor (RXR) agonists with regard to growth inhibition and differentiation induction in monoblastic leukemia cells. Biochem Pharmacol 57: 521-529, 1999
Honma Y, Tobe H, Makishima M, Yokoyama A, Okabe-Kado J. Induction of differentiation of myelogenous leukemia cells by humulone, a bitter in the hop. Leuk Res 22: 605-610, 1998
Kanatani Y, Makishima M, Ishikawa I, Ogasawara Y, Kawahara N, Motoyoshi K, Nagata N, Honma Y. A novel uracil analog, 6-chloro-5-(2-propenyl) uracil preferentially enhances growth inhibition and differentiation of myeloid leukemia cells induced by 1alpha,25 dihydroxy vitamin D3. Exp Hematol 26: 198-206, 1998
Makishima M, Umesono K, Shudo K, Naoe T, Kishi K, Honma Y. Induction of differentiation in acute promyelocytic leukemia cells by 9-cis retinoic acid alpha-tocopherol ester (9-cis tretinoin tocoferil). Blood 91: 4715-4726, 1998
Makishima M, Okabe-Kado J, Honma Y. Growth inhibition and differentiation induction in human monoblastic leukaemia cells by 1alpha-hydroxyvitamin D derivatives and their enhancement by combination with hydroxyurea. Br J Cancer 77: 33-39, 1998
Makishima M, Honma, Y. Tretinoin tocoferil as a possible differentiation-inducing agent against myelomonocytic leukemia. Leuk Lymphoma 26: 43-48, 1997
Kanatani Y, Makishima M, Asahi K, Sakurai A, Takahashi N, Motoyoshi K, Nagata N, Honma Y. Differanisole A, a novel antitumor antibiotic, enhances growth inhibition and differentiation of human myeloid leukemia cells induced by 9-cis retinoic acid. Biochim Biophys Acta 1359; 71-79, 1997
Yamamoto-Yamaguchi Y, Makishima M, Kanatani Y, Kasukabe T, Honma, Y. Reversible differentiation of human monoblastic leukemia U937 cells by ML-9, an inhibitor of myosin light chain kinase. Exp Hematol 24; 682-689, 1996
Makishima M, Honma Y. Ethacrynic acid and 1alpha,25-dihydroxyvitamin D3 cooperatively inhibit proliferation and induce differentiation of human myeloid leukemia cells. Leuk Res 20: 781-789, 1996
Makishima M, Kanatani Y, Yamamoto-Yamaguchi Y, Honma, Y. Enhancement of activity of 1alpha,25-dihydroxyvitamin D3 for growth inhibition and differentiation induction of human myelomonocytic leukemia cells by tretinoin tocoferil, an alpha-tocopherol ester of all-trans retinoic acid. Blood 87: 3384-3394, 1996
Makishima M, Yamamoto-Yamaguchi Y, Honma Y. 19-Allylaminoherbimycin A, an analog of herbimycin A that is stable against treatment with thiol compounds or granulocyte-macrophage colony-stimulating factor in human leukemia cells. Biochim Biophys Acta 1272; 199-205, 1995
Makishima M, Honma Y, Hozumi M, Sampi K, Motoyoshi K, Nagata N, Hattori M. Differentiation of human myeloblastic leukemia ML-1 cells into macrophages by staurosporine, an inhibitor of protein kinase activities. Exp Hematol 21; 839-845, 1993
Makishima M, Honma Y, Hozumi M, Nagata N, Motoyoshi K. Differentiation of human monoblastic leukemia U937 cells induced by inhibitors of myosin light chain kinase and prevention of differentiation by granulocyte-macrophage colony-stimulating factor. Biochim Biophys Acta 1176; 245-249, 1993
Suzu S, Ohtsuki T, Makishima M, Yanai N, Kawashima T, Nagata N, Motoyoshi, K. Biological activity of a proteoglycan form of macrophage colony-stimulating factor and its binding to type V collagen. J Biol Chem 267; 16812-16815, 1992
Makishima M, Honma Y, Hozumi M, Sampi K, Hattori M, Ishikawa I, Ogura H, Motoyoshi K. Effects of novel uracil analogs on proliferation and differentiation of human myeloid leukemia cells. Exp Hematol 20; 879-885, 1992
Makishima M, Honma Y, Hozumi M, Sampi K, Hattori M, Motoyoshi K. Induction of differentiation of human leukemic cells by inhibitors of myosin light chain kinase. FEBS Lett 287; 175-177, 1991
Makishima M, Honma Y, Hozumi M, Sampi K, Hattori M, Ishikawa I, Ogura H, Kawahara N, Kanaiwa T, Motoyoshi K. Induction of differentiation of human myeloid leukemia HL-60 cells by novel pyrimidine nucleoside analogs. Biochim Biophys Acta 1094; 1-7, 1991
Makishima M, Honma Y, Hozumi M, Sampi K, Hattori M, Umezawa K, Motoyoshi K. Effects of inhibitors of protein tyrosine kinase activity and/or phosphatidylinositol turnover on differentiation of some human myelomonocytic leukemia cells. Leuk Res 15; 701-708, 1991
